Articles » Links between white matter integrity, eye movement function, and health in postconcussion syndrome
Links between white matter integrity, eye movement function, and health in postconcussion syndrome
Introduction
Postconcussion syndrome (PCS) can affect up to 20-30% of patients with mild closed head injury (mCHI), comprising the prolonged and disabling persistence of postconcussional symptoms. Previous studies [1,2] have identified eye movement function at 1 week post-injury as a possible predictive marker for PCS, showing that mCHI patients who later develop PCS manifest measurable differences in eye movement function compared to mCHI patients of similar injury status who later show a good recovery. This study examined the relationship of oculomotor function with structural brain integrity as measured by diffusion tensor imaging (DTI) at 1 week after mCHI. The study focused on the contrast between patients who later (i.e., at 3 months post-injury) met the diagnostic criteria for PCS and patients with good recovery. This is the first study to examine the relationship between eye movement function and imaging evidence of brain injury in the context of eye movement control after mCHI.
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